Searchable abstracts of presentations at key conferences in endocrinology

ea0079003 | Abstracts | BES2021

Gene expression signatures of target tissues in endocrine and non-endocrine autoimmune diseases. Présenté par Prof. Miriam Cnop

F Szymczak , M. L. Colli , M. J. Mamula , C Evans-Molina , D. L Eizirik

Objectives: Autoimmune diseases are typically studied with a focus on the immune system, and less attention is paid to responses of target tissues exposed to the immune assault. We aimed to evaluate, based on available bulk RNA sequencing data, whether inflammation induces similar molecular signatures in the target tissues of five autoimmune diseases, namely type 1 diabetes (T1D), Hashimoto’s thyroiditis (HT), rheumatoid arthritis (RA), multiple sclerosis (MS) and systemi...